These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. How to come off hydroxychloroquine Plaquenil polymyalgia rheumatica In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. The review is based on 57,733 people who have side effects while taking the drug from Food and Drug Administration FDA. The information that eHealthMe analyzes includes Tell your doctor right away if you have any serious side effects, including arm/leg/back pain, slow heartbeat, symptoms of heart failure such as shortness of breath, swelling ankles/feet. Hello,i have had an increased heart rate since I was put on plaquenil-generic and my rheumatologist said that is not a side effect from the heart rate used to run 60 to 74 bpm and now up to 104 daily and with exercise like the treadmill it raises to 178 which is dangerous. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil side effects heart HYDROXYCHLOROQUINE - ORAL Plaquenil side effects., Plaquenil Oral Uses, Side Effects, Interactions. The best way to taper off plaquenilHydroxychloroquine 200 mg overdoseWhy do some supplements call generic hydroxychloroquine brand name Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. Rapid Heartbeat with Plaquenil - Lupus - MedHelp. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Many doctors disagree about the effects of plaquenil on the arthritis. It does help in about 60 % of the cases of arthritis by significantly reducing the pain. However, about 20 – 30 percent of people stop using it because of the side effects. Side effects include digestive problems, skin rash and disorders of skin pigmentation.