It is estimated that as many as 8 million people in Mexico, Central America, and South America have Chagas disease, most of whom do not know they are infected. If untreated, infection is lifelong and can be life threatening. Plaquenil eye risks Chloroquine nurses responsibility Chagas disease is named after the Brazilian physician Carlos Chagas, who discovered the disease in 1909. It is caused by the parasite Trypanosoma cruzi, which is transmitted to animals and people by insect vectors and is found only in the Americas mainly, in rural areas of Latin America where poverty is widespread. Chagas disease T. cruzi infection is also referred to as American. A person carrying one gene for sickle-cell hemoglobin will be resistant to Plasmodium infection. T/F Treatment for Chagas disease is recommended for people diagnosed early in the course of infection acute phase, babies with congenital infection, and for those with suppressed immune systems. Many patients with chronic infection may also benefit from treatment. Patients should consult with their primary health-care provider. Large-scale population movements from rural to urban areas of Latin America and to other regions of the world have increased the geographic distribution and changed the epidemiology of Chagas disease. The impact of Chagas disease is not limited to only rural areas of Latin America in which vectorborne transmission (diseases transmitted by insects) occurs. Chagas disease is treated with chloroquine t f Chagas Disease Symptoms, Treatment & Diagnosis, Parasitology & Mycology Exam 1 Dr Lu Flashcards Quizlet Mechanism of hydroxychloroquineHow do you say plaquenilWhat can plaquenil treatChloroquine concentration transfection This chapter discusses Chagas' disease. Trypanosoma cruzi, which is the protozoan parasite causing Chagas' disease, represents the most significant health problem in the American continent in terms of human health, socioeconomic impact, and geographic distribution. This parasite also affects a large number of mammalian species. Chagas' Disease American Trypanosomiasis - ScienceDirect. CDC - Chagas Disease - Treatment. Agrochemicals against Malaria, Sleeping Sickness.. Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the protist Trypanosoma cruzi. It is spread mostly by insects known as Triatominae, or "kissing bugs". The symptoms change over the course of the infection. In the early stage, symptoms are typically either not present or mild, and may include fever, swollen lymph nodes, headaches, or local. Trypanosoma cruzi, the agent of Chagas' disease, is treated with nifurtimox, a nitrofuran derivative. It is given orally and results in the production of activated forms of oxygen, which are lethal to the parasite. Other forms of trypanosomiasis African trypanosomiasis, or sleeping sickness are caused by T. brucei gambiense or T. brucei. Treatment. Treatment for Chagas disease focuses on killing the parasite and managing signs and symptoms. During the acute phase of Chagas disease, the prescription medications benznidazole and nifurtimox may be of benefit.