Please review the following URL and make sure that it is spelled correctly. Anita- It is hard to say whether I noticed a difference when I first went on plaquenil, because I was also on 10mg of prednisone at that time, and I didn't start weaning down from that until I had been on plaquenil for a few months. Reviews on hydroxychloroquine Teva chloroquine 250 mg Does hydroxychloroquine decrease human anti-chimeric antibody What is the genetic cause of chloroquine resistance Discontinuation of hydroxychloroquine could decrease hydrocodone plasma concentrations, decrease opioid efficacy, and potentially lead to a withdrawal syndrome in those with physical dependence to hydrocodone. Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Find information about common, infrequent and rare side effects of Plaquenil Oral. To answer some of your other questions, it was the same timeframe for me. I can say that the prednisone wean was successful, even after having only been on plaquenil a few months. Plaquenil discontinuation syndrome PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION, Plaquenil Withdrawal – Life As An Anomaly Is plaquenil safe to takePlaquenil fever If any severe blood disorder such as aplastic anemia, agranulocytosis, leukopenia, or thrombocytopenia, appears which is not attributable to the disease under treatment, consider discontinuation of Plaquenil. Plaquenil should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Plaquenil - FDA prescribing information, side effects and uses. Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Nov 14, 2006 Someone else told me that plaquenil could take up to a year to work. Others have told me that it only took a few months for them to feel the effects. Everyone is different. I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the. Jul 12, 2015 Polymyalgia Rheumatica Plaquenil hydroxychloroquine Withdrawal Pain Jul 12, 2015. I saw my Rheumy last week and he is concerned about my being up to 9mg of pred for the past 5 months from 4mg.