Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil retinal screening Hydroxychloroquine to stop flare ups Plaquenil is also an option for those who try and fail biologic drugs, cannot tolerate biologics or fear potential side effects linked to biologic DMARDs. How It Works Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It belongs to a class of medications known as disease-modifying antirheumatic drugs DMARDs. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Antiboptics and plaquenil Plaquenil & other drug interactions ? Lupus Forums at The., Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil octPlaquenil causes lowcalcium levelsChloroquine colon cancerHydroxychloroquine retinopathy and night visionHydroxychloroquine and ocular toxicity recommendations on screening 2009 Antibiotics Home Plaquenil Interactions Plaquenil Interactions When phenothiazine medications, certain beta blockers, or certain parasite medicines are taken together with Plaquenil, interactions can occur that may affect the drug levels in your blood. Plaquenil Interactions - Antibiotics Home Page. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Can Plaquenil be taken with antibiotics? - Page 2. Hydroxychloroquine Plaquenil Chloroquine Aralen Quinacrine Atabrine What are anti-malarial drugs, and why are they used to treat lupus? Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. Plaquenil and belong to different drug classes. Plaquenil is an antimalarial medication and prednisone is a glucocorticoid. Side effects of Plaquenil and prednisone that are similar include nausea, vomiting, or headache. Plaquenil is used to treat other types of infections too. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk.