Chloroquine treatment in pregnancy

Discussion in 'Plaquenil Generic' started by ayc, 18-Mar-2020.

  1. Bezyan Guest

    Chloroquine treatment in pregnancy

    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    For pregnant women diagnosed with uncomplicated malaria caused by P. malariae, P. vivax, P. ovale, or chloroquine-sensitive P. falciparum infection, prompt treatment with chloroquine treatment schedule as with non-pregnant adult patients is recommended. Alternatively, hydroxychloroquine, may be given instead. Chloroquine, although grouped with hydroxychloroquine in table 2 of this article, is not routinely used in the management of SLE either in or out of pregnancy due to increased tissue deposition and increased risk of retinal toxicity and of fetal abnormalities 10 - 11. We postulated that intermittent preventive treatment in pregnancy with chloroquine or weekly chloroquine chemoprophylaxis would be superior to intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine in preventing placental malaria infection and the maternal and newborn adverse effects of pregnancy-associated malaria.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine treatment in pregnancy

    Treatment of Malaria While Pregnant –, Treatment of SLE in pregnancy and use of Chloroquine The BMJ

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  7. Intermittent preventive treatment of malaria in pregnancy IPTp with sulphadoxine-pyrimethamine SP reduces the incidence of low birth-weight, pre-term delivery, intrauterine growth-retardation and maternal anaemia. However, the public health benefits of IPTp are declining due to SP resistance.

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    It appears to be safe for use during pregnancy. Chloroquine is a member of the drug class 4-aminoquinoline. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. Summary. Aralen is the brand name for the generic drug chloroquine, an anti-malaria drug used to treat malaria and amebiasis infection that's spread outside of the intestines. Dosage, drug interactions, and pregnancy and breastfeeding safety information should be reviewed prior to taking this drug. Chloroquine may be used throughout pregnancy for the prophylaxis and treatment of malaria. If chloroquine resistance of the parasite is likely or has been demonstrated, other drugs must be used.

  8. rmarkov XenForo Moderator

    Reportedly 64 percent of infections that occur in patients with RA occur in the foot and ankle. Medications to Discontinue Before Surgery – Pre-Operative. Before Your Root Canal Surgery Preparing for Your Treatment. Can Plaquenil Be Taken Before Or After A Surgery? - Page 5
  9. jkasdsfanmkim XenForo Moderator

    I've been on plaquenil for 6 months now and I still have significant joint pain! After being so glad about having a rheumy that listens I am almost afraid to go in and say "its not working" for fear she will say.... bye" And I did something incredibly stupid last month. So I did and my joints flared (and my nausea got worse) and I felt terrible (fevers, rashes, mouth/nose ulcers, fatigue). Myalgia 6 Common Reasons for Experiencing Muscle Pain. Hydroxychloroquine Plaquenil Lupus Do you still have joint and muscle pain on plaquenil?
  10. NNew User

    In Vitro Antiviral Activity and Projection of Optimized. Based on PBPK models results, a loading dose of 400 mg twice daily of hydroxychloroquine sulfate given orally, followed by a maintenance dose of 200 mg given twice daily for 4 days is recommended for SARS-CoV-2 infection, as it reached three times the potency of chloroquine phosphate when given 500 mg twice daily 5 days in advance.

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