It says on the bottle I can’t take an antacid for at least four hours after taking the Plaquenil. I hate heart burn:( I take a PPI (proton pump inhibitor) essentially antacid in the morning that is supposed to last all day. I would ask your pharmacist first and see if it matters whether it is just a 'tums' or medication strength. I think if it keeps happening I’ll go talk to my pharmacist to see what they recommend. Has anyone else experienced heartburn while taking Plaquenil and if so what did you do to avoid or ease the heartburn? If they are not able to give you an answer your Family Dr or Rheumatoid will know. Fortunately the heartburn goes away after a few hours, but those few hours are very uncomfortable! Hydroxychloroquine liver function tests Chloroquine retinal screening Plaquenil 200 mg effets secondaires As far as I know the advice is to make sure that antacids and Plaquenil are taken at least 4 hours apart. If they are taken together - effectiveness decreases but 4 hours apart is OK. Take care - Scottie A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Today on WebMD. Medications That Make You Tired. Two days now I've taken the Pepcid, then an hour later took the Plaquenil and it's working great. I didn't even eat this morning and didn't have a problem. BTW I talked to two pharmacists and both said that it's okay to take with the plaquenil. But that's just the optimum way to take it, not the necessity. Sometimes what is suggested (no antacid for 4 hours) is not necessarily required if it means you can't or don't want to take your plaquenil anymore. the antacid will affect the absorption of the plaquenil and the amount your body can absorb. Can i take tums with plaquenil Stomach problems with Plaquenil • Johns Hopkins Arthritis Center, Nortriptyline Oral Interactions with Other Medication Ocular toxicity hydroxychloroquineUsing pei vs chloroquineHydroxychloroquine male fertilityHydroxychloroquine price costcoChloroquine off label use Can I take zantac while taking methotrexate and plaquenil? Asked by margmac Updated 13 January 2015 Topics plaquenil, zantac, rheumatoid arthritis, methotrexate, antacid, stomach, contraindication. I have an acid stomach and need to take an antacid need help to choose one that won't be a contraindication. Can I take zantac while taking methotrexate and plaquenil?. Plaquenil and Pepcid -. Plaquenil and heartburn rheumatoid. An interesting thing is that antacids like Tums can interact with acid reducers making the acid reducer less effective. So don't take anything for granted when looking up interactions, and look up all your over the counter OTC medications, as well. If you think this requires changes in timing or dosage. Feb 19, 2020 Avoid taking an antacid or Kaopectate kaolin-pectin within 4 hours before or after you take hydroxychloroquine. Some antacids can make it harder for your body to absorb hydroxychloroquine. What other drugs will affect hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox? Hydroxychloroquine can cause serious liver or heart problems, especially if you use certain medicines at the same time, including other medicines to treat malaria; an antibiotic or antifungal medicine; antiviral. I take omeprazole Prilosec, a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug? Answer Omeprazole Prilosec, Nexium, and other proton pump inhibitor drugs can be affected by taking supplements, and can affect your ability to absorb certain vitamins and minerals. St.