Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Omphthamologists risks of hydroxychloroquine Hydroxychloroquine deafness Compare Chloroquine vs Hydroxychloroquine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Chloroquine rated 10.0/10 vs Hydroxychloroquine rated 6.7/10 in overall patient satisfaction. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Drug interactions between hydroxychloroquine Digoxin oral and hydroxychloroquine oral Drug Interactions., Hydroxychloroquine Uses, Dosage & Side Effects - Plaquenil for lichen planopilaris Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Drug Interaction Checker - Find Interactions Between Medications. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Drug Interactions. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Renal failure and certain drug interactions such as interactions with tamoxifen, glycosides, methotrexate and ciclosporin can influence the pharmacokinetics of hydroxychloroquine and chloroquine.