Chloroquine malaria in wwii

Discussion in 'Northwest Pharmaceuticals Canada' started by dragon99, 12-Mar-2020.

  1. Tema323 User

    Chloroquine malaria in wwii


    Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    Chloroquine might be getting new life as an antiviral treatment for the novel coronavirus that emerged in Wuhan, China in late 2019 and has infected some 25,000 people in more than 25 countries. For decades, the drug was a front-line treatment and prophylactic for malaria. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Following the war, chloroquine and DDT emerged as the two principal weapons in WHO’s global eradication malaria campaign. Subsequently, chloroquine resistant P. falciparum probably arose in four separate locations starting with the Thai-Cambodian border around 1957; in Venezuela and parts of Colombia around 1960; in Papua New Guinea in the mid-1970s and in Africa starting in 1978 in Kenya and Tanzania and spreading by 1983 to Sudan, Uganda, Zambia and Malawi.

    Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria.

    Chloroquine malaria in wwii

    Chloroquine Aralen - Side Effects, Dosage, Interactions., Treating Lupus with Anti-Malarial Drugs Johns Hopkins.

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  7. The Allied push to synthesize antimalarial agents during World War II was prompted by Japan's seizure of Java in 1942. At the time, 90% of the world's quinine came from Java. Allied interest in chloroquine followed the capture of German supplies of an analogue called sontoquine in Tunis in 1943.

    • Role of US Military Research Programs in the Development..
    • History of antimalarials Medicines for Malaria Venture.
    • Antimalarial Drugs – Malaria Site.

    Malaria in World War II Conditions in the South Pacific Theater during World War II were harsh — thick jungle, high temperatures, heavy rainfall, swamps, excessive mud, and mountainous terrain made life difficult enough for Soldiers. Quinine is an effective antimalarial, and has relatively few side effects that tend to be mild in nature. As a result, it was the preferred medicine used by the Army for treating malaria. As World War II approached, the world supply of quinine was largely under control of the Netherlands. As regards antimalarial drugs, World War II liberated us from quinine, taught us how to use Atabrine, and led us to such powerful new antimalarials as chloroquine and amodiaquin, primaquine, proquanil, and pyrimethamine.

     
  8. LePReZeNT Guest

    Hi everyone, I am wondering if anyone has had a problem with fatigue while on Plaquenil. At first, I was nauseous for a week or so, which the dr. After the nausea went away it seemed like my pain got worse for a week or so, and then it gradually got better. I am also bothered with stomach cramps and mild diarrhea. Rheumatoid Arthritis and Sleep Arthritis Foundation Is extreme fatigue a side effect of Plaquenil - NRAS Hydroxychloroquine MedlinePlus Drug Information
     
  9. abalaban New Member

    Yaz and Plaquenil drug interactions - eHealthMe It is often used in birth control. Check the latest outcomes from 40,196 Yaz users, or browse all drugs. What is Plaquenil? Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. Check the latest outcomes from 50,877 Plaquenil users, or browse all drugs.

    Contraception for adolescents with lupus
     
  10. solomonxxx Well-Known Member

    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus What are the possible side effects of antimalarial drugs? Plaquenil is most often well-tolerated but, like with any drug, side effects are possible. Most people about 90% who take antimalarial medications experience no side effects. If common side effects do occur, they are usually minor and last only for a short period of time.

    Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol.