Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Primaquine chloroquine Hydroxychloroquine sulfate vs hydroxychloroquine The alternative to Plaquenil is a slightly different anti malarial called Quinacrine. Plaquenil replaced Quinacrine formerly called Atabrine for anti malarial prophylaxis so now the Quinacrine has to be made up into pills or gel capsules by a compounding pharmacy. If you google you will find details of compounding pharmacies. There are several drugs now that you can take instead of the plaquenil. these type of drugs they have now work in a different way then the methotrexate and plaquenil. most of these drugs you will still take the methotrexate. i researched these drugs before i made my decision and so for myself i started on the enbril and boy what a because of insurance issues from aug 09 until. Head-to-head comparisons of medication uses, side effects, ratings, and more. Treats malaria and autoimmune conditions including rheumatoid arthritis and lupus. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil and other medications Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Is there a drug that I can take to replace plaquenil? Plaquenil and liver problems Plaquenil is used to treat other types of infections too. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Compare Plaquenil vs Chloroquine -. Plaquenil hydroxychloroquine Alternatives & Similar Drugs -. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. You will likely have to take additional medications to keep your rheumatoid arthritis in control. DMARDs include methotrexate, sulfasalazine, leflunomide Arava®, etanercept Enbrel®, infliximab Remicade®, adalimumab Humira®, certolizumab pegol Cimzia®, golimumab Simponi®, abatacept Orencia®, rituximab Rituxan®, tocilizumab Actemra®, anakinra Kineret®, antimalarials e.g. Plaquenil®.