It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Chloroquine hydrochloride physicochemical properties Chloroquine diphosphate salt lysosome inhibitor Sep 12, 2008 Hi all, I am a newbie. I am a 33 year old with Lupus, in remission for the last 5 years, and generally healthy. I met with my high-risk OBGyn today not yet pregnant but hoping soon and she suggested that since I have been in remission for the last 5 years, that I might want to think about going off my plaquenil before trying to get pregnant. I found out that I was pregnant at 6 months into the pregnancy. Which means I'd been on Plaquenil for the whole thing. My rheumatologist said it was fine, and my perinatologist freaked out. Basically, Plaquenil hasn't been studied on pregnant women because you CAN'T test it on pregnant women. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and pregnancy UpToDate, Has anyone taken Plaquenil. — The Bump Plaquenil helps.me.sleepPlaquenil and pvcBenefits of taking plaquenilChloroquine phosphate for sale Is plaquenil safe to take during pregnancy? I've heard yes from some doctors and no from others. My rheumie says that although it has been proven safe, once he finds out that I'm pregnant he's going to take me off of it. Pregnancy and Plaquenil - HealthBoards. Hydroxychloroquine Use During Pregnancy. Things You Didn't Know about Lupus & Pregnancy. The anti-malarial drugs Hydroxychloroquine HCQ is widely used to treat various rheumatic diseases mechanism of action of this drug is to increase the pH in acidic vesicles, inhibiting receptor mediated endocytosis that affects many cellular functions including antigen presentation, toll receptor signaling and post-transcriptional modification of proteins 2–4. The best time to be pregnant is when you are doing well with your health. Women whose lupus is in remission have much less trouble with pregnancy than women whose disease is active. It is strongly recommended that you meet with your doctor three to six months in advance of when you plan to try to become pregnant. Objective. To investigate the effect of hydroxychloroquine HCQ in pregnant women with systemic lupus erythematosus SLE. Methods. In SLE pregnancies of a single Dutch center 2000–2015, lupus activity and flares before and during pregnancy and postpartum were assessed using the SLE Disease Activity Index SLEDAI/SLEPDAI SLEDAI adjusted for pregnancy.