It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine in real life Sar of chloroquine Chloroquine ototoxicity How to stop itching from plaquenil So, I've read the half-life is from 30-60 days. That is one of the reasons I didn't want to take it - that's a long time to stick around. I did read hair loss, photosensitivity, itching area all potential side effects of Plaquenil, so hopefully those will subside soon as the med levels drop. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil long term use side effects Plaquenil Side Effects on Your Eyes and Vision, The Risk of Retinal Toxicity with Plaquenil Cutaneous hyperpigmentation during therapy with hydroxychloroquineChanges in taste and smell caused by hydroxychloroquineWhy would plaquenil not work on raPlaquenil causing psoriasisLong term chloroquine prophylaxis Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. The review is based on 57,733 people who have side effects while taking the drug from Food and Drug Administration FDA. The information that eHealthMe analyzes includes Visual changes and loss of vision are potential hydroxychloroquine side effects, although they most commonly occur in individuals who have taken high doses of hydroxychloroquine for long periods. Physicians will generally recommend an eye exam every six months for patients taking hydroxychloroquine long-term. Long term studies have shown a high rate of termination of hydroxychloroquine treatment in patients with RA. Although it has been shown that discontinuation of treatment with hydroxychloroquine is associated with exacerbation of SLE, long term maintenance rates of treatment with hydroxychloroquine in patients with SLE have not been investigated.