It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system. I had almost (but not quite) forgotten what these aches and pains feel like, but they're back…I am re-acquainting myself with those symptoms that it tames: the overall flu-like and feverish feeling -- aka malaise -- and joint pain." (Click here to read more). I had a similar experience when I stopped taking plaquenil. Alternative meds than plaquenil Photoreceptor integrity line plaquenil Hydroxychloroquine drug interactions Chloroquine cell effect Jun 11, 2013 For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system. The first dose of Plaquenil is usually taken one to two weeks before traveling to an area where malaria is prevalent. Doses are then continued for four weeks after exposure. Plaquenil generic name hydroxychloroquine is one of the few medications that is regularly prescribed for Sjogren’s Syndrome, despite the fact that it has not been approved for SS by the FDA, so any use is off-label. While clinical trials for it’s effectiveness have been mixed. My joint and muscle pain went up and my energy levels went down. No, but it did alleviate some of the symptoms and improve my quality of life. It was one of those situations where I didn't realize the medication was having such an impact until I stopped it. Plaquenil dosage for sjogrens Plaquenil dosage -, Plaquenil Hydroxychloroquine - Side Effects, Dosage. 2d chemical structure of chloroquineSle plaquenil with methotrexateHydroxychloroquine for vasculities rashSide effects of plaquenil 200 mg tablets Once corticosteroids have been started, the patient is usually seen 1-3 months. Depending on the patient's condition, the dosage can be tapered at those visits. After 3-6 months, the dose should be tapered to physiolog- ic levels – for example, 10 mg of prednisone per day or less. SARCOIDOSIS TREATMENT GUIDELINES. Plaquenil toxicity and lowering dosage What You Sjo. Plaquenil Dosage Guide -. Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. It’s used in people with Sjogren’s syndrome, rheumatoid arthritis, and lupus to relieve joint pain, fatigue, and rashes. It may take up to 12 weeks for you to notice the effects of hydroxychloroquine. Hydroxychloroquine is safe, even for pregnant women with Sjogren’s syndrome. Hydroxychloroquine is the most widely prescribed treatment in the U. S. to manage fatigue in Sjogren’s syndrome, but this practice is largely made based on clinical experience. Disclosures Development of the guidelines was done with support from the Sjogren’s Syndrome Foundation.