Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil not working Plaquenil and metoprolol What vitamins should i supplement if i am taking plaquenil Autophagy inhibition by chloroquine CQ sensitizes colon cancer cells to hypoxia and oxaliplatin. Inhibition of autophagy by chloroquine sensitizes colon cancer cells to oxaliplatin under oxic and hypoxic conditions. HT29 cells were tested for the effect of autophagy inhibition by chloroquine. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine colon cancer Dissecting pharmacological effects of chloroquine in cancer., Chloroquine Indications, Side Effects, Warnings - Hydroxychloroquine sulfate tabletsChloroquine take how long to work Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Chloroquine - Wikipedia. Hydroxychloroquine Oral Route Description and Brand Names - Mayo Clinic. Chloroquine Side Effects Common, Severe, Long Term -. Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells Article PDF Available in BMC Cancer 101370 July 2010 with 253 Reads How we measure 'reads' The Chloroquine Story in Cancer Continues By Derek Lowe 10 February, 2016 Almost immediately after Pfizer and Novartis provided evidence that chloroquine used in several chemotherapy regimes doesn’t do what people thought, another drug company AstraZeneca, along with coworkers at Dundee is out with a paper suggesting what it might be. Chloroquine CQ, the worldwide used anti-malarial drug, has recently being focused as a potential anti-cancer agent as well as a chemosensitizer when used in combination with anti-cancer drugs. It has been shown to inhibit cell growth and/or to induce cell death in various types of cancer.