B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Does hydroxychloroquine require a prescription Plaquenil malaria dosage Difference between methotrexate and plaquenil Plaquenil dry eyes Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Before taking hydroxychloroquine, tell your doctor and pharmacist if you are allergic to hydroxychloroquine, chloroquine Aralen, primaquine, or any other drugs. tell your doctor and pharmacist what prescription and nonprescription drugs you are taking, especially acetaminophen Tylenol, others, digoxin Lanoxin. Mar 08, 2019 Thiol-containing drugs are the most common cause of pemphiguslike reactions see Oral drug-reaction patterns and associated drugs and drug classes in Introduction. In drug-induced pemphigus vulgaris, the relatively fragile vesicles are rarely observed at clinical examination, and most cases are characterized by irregular ulcerations with ragged borders that may coalesce to involve large areas of the mucosa. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Plaquenil medication oral pigmentation Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Hydroxychloroquine MedlinePlus Drug Information Chloroquine suicide survivorPlaquenil ankylosing spondylitis Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Skin Pigmentation with Hydroxychloroquine Plaquenil.. Oral Manifestations of Drug Reactions Overview, Xerostomia.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Inactive Ingredients Dibasic Calcium Phosphate, Hydroxypropyl Methylcellulose, Magnesium Stearate, Polyethylene glycol 400, Polysorbate 80, Corn Starch, Titanium Dioxide. Patients with HCQ-induced pigmentation had a higher frequency of associated antiphospholipid syndrome 8 patients 33% vs 84 control patients 16%; P =.046 and were more frequently treated with oral anticoagulants 9 patients 38% vs 67 control patients 13%; P =.003 or antiplatelet agents 14 patients 58%.