Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? What class of drug is hydroxychloroquine sulfate How long until hydroxychloroquine works If you go to or rxlist.com, neither of them list weight gain as a side effect, while they both list "nausea, vomiting, stomach pain; loss of appetite, weight loss" as side effects. During trials, if any adverse event read possible side effect occurs, and the company can't prove it wasn't the drug, it goes on the list as a side effect. I've been taking hydroxychloroquine since last Autumn - dose increased to 400 mg per day in April. I think it helps me, but it can take 6 months to kick in. Still have to be really careful not to get over-tired. Can give you wind and stomach bloating. However, in some people hydroxychloroquine can cause skin rashes, especially those made worse by sunlight. feeling sick nausea or indigestion. diarrhoea. headaches. bleaching of the hair or mild hair loss. tinnitus ringing in the ears. visual problems. My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Hydroxychloroquine side effects weight loss Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., How good is Hydroxychloroquine, and any side effe. Hydroxychloroquine sulfate 200 mg tabletCan use of plaquenil have effect on vaccinations years laterPlaquenil and fevers Nov 09, 2018 Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Hydroxychloroquine Side-effects, uses, time to work. Abnormal Weight Gain and Gut Microbiota Modifications Are.. Loss of appetite; mood changes; no pulse or blood pressure; numbness or tingling in the hands, feet, or lips; unconsciousness; Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.