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I gained 40 pounds while taking Zoloft and yet I can't cope without some sort of medication nor can I cope with this weight gain. I have just switched to Wellbutrin XL because I heard it doesn't cause that weight gain that Zoloft does... Can someone pleae tell me if they have gone through this and what I should expect? I just tried Wellbutrin because I read that it had fewer side effects than others and may help lose weight (and I had just tried Cymbalta and Effexor and didn't like the side effects)... I was a little hesitant to try Wellbutrin since I had success with Prozac in the past, which works on Serotonin (like Zoloft) and Wellbutrin works on Dopamine (a completely different drug)..I have to say, after 3 tough weeks of severe nausea, lightheadedness, dizziness, headaches, and dry mouth, I had to stop Wellbutrin and will be going back to prozac. If Zoloft helped with your depression, than there is a chance Wellbutrin won't work, because the brain chemistry problem that needs to be addressed is the serotonin problem. Wellbutrin CAN be helpful even when people have previously had a good response to an SSRI (Zoloft, Prozac, Paxil, Lexapro, etc.). Antabuse generic name Tamoxifen brain fog Azithromycin z pack 5 day Zoloft sertraline generic is a prescription drug used to treat depression, obsessive-compulsive disorder, panic disorder, PTSD, social anxiety disorder, and PMDD. Common side effects are dizziness, insomnia, nervousness, and sleepiness. Drug interactions and pregnancy and breastfeeding safety information are included. Zoloft is an SSRI selective serotonin reuptake inhibitors antidepressant prescribed for the treatment of depression, obsessive compulsive disorder, panic disorder, posttraumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. Zoloft is available as a generic drug. Common side effects of Zoloft include. I was on Wellbutrin for depression for 2 days when I started feeling really really down and depressed more than usual. I thought it was just me adjusting to the meds but on the 3rd day I had a horrible panic attack, to the point i thought i was dying. I have been taking generic Wellbutrin 450mg for the past couple of years combined with generic Zoloft 50mg. I have never had good results and every other antidepressant I have tried has made me terribly drowsy. I have Graves' disease on top of severe anxiety and depression. I recently read on another blog that Brand-name Wellbutrin works better for some people, so I talked to my psychiatrist about changing to brand-name. Since I switched to brand-name on both the Wellbutrin and Zoloft I have felt much better. But now that I have been taking that for about 3 months, I have started to feel very apathetic, I can't seem to get myself out of the bed in the morning, almost "zombie"-like. I don't feel depressed and I'm certainly not anxious... Is it possible thhat , since the brand-name has been more effective, maybe I should decrease my dosage?? By Tammy Preston, MS Generic Name: Bupropion (bew-PROH-pee-on) Brand Names: Wellbutrin®, Zyban®, Budeprion®, Aplenzin®, Voxra® Manufacturers: Glaxo Smith Kline Inc. Wellbutrin® is an antidepressant that has shown promise in helping people with childhood and adult ADHD. Antidepressants are sometimes used in conjuction with stimulants (such as Adderall) or as a standalone treatment for sufferers of adult attention deficit hyperactivity disorder. As well, depression and adult ADHD often coexist, and this medication is useful for people dealing with both issues. It is not known exactly how Wellbutrin® works, but it is thought that it inhibits the reuptake to norepinephrine and dopamine, which creates feelings of enjoyment and motivation. Normally Wellbutrin® XR (extended release) is used as this ensures the medication remains effective all day, as well as reduces incidences of side effects. In a double-blind, placebo-controlled, randomized trial of 40 patients, Wellbutrin® showed a statistically significant effect in improving symptoms of people with adult ADHD. That being said, Wellbutrin® is normally on tried after stimulants such as Adderall have been tried as stimulants are normally more effective in treating adult ADHD. Wellbutrin® Side Effects The biggest side effect of Wellbutrin® is the possibility of seizures. This risk is mitigated by using the lowest possible effective dose. Pregnancy Category C Women who are pregnant or may become pregnant should not use Wellbutrin®. Zoloft vs wellbutrin Compare Wellbutrin vs Zoloft - Treato, Common Side Effects of Zoloft Sertraline Hcl Drug Center. 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Wellbutrin bupropion and Zoloft sertraline are antidepressants used for the management of major depression Wellbutrin is also used to treat seasonal.