It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Plaquenil maintenance dose Chloroquine and neuropathy Plaquenil arthritis meds Chloroquine and proguanil brand I have to take mine separate and each time with food. Otherwise they make me really sick and nauseous too. I take most of my meds spaced out through the day 4x per day now down from 6x and with food in order to minimize the side effects and get the junk in me. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Take this medicine with meals or milk to lessen stomach upset, unless otherwise directed by your doctor. Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon. For patients taking hydroxychloroquine to prevent malaria Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Best time to take hydroxychloroquine Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Taking Plaquenil for Rheumatoid Arthritis The trade name of chloroquine isRemission with plaquenil Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking this medicine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. I take 200mgs in the morning with breakfast and the other 200mgs with my dinner at 5 pm, as long as i eat enough i don't get any side effects. when i was on it about 7 years ago, i was told by the Dr to take it at night only, and i guess i did'nt take it with enough food cos i use to get terrible gas and my stomach hurt. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients.