Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine 12.5mg Hydroxychloroquine for vasculities rash What was hydroxychloroquine originally used for Plaquenil prevent antiphospholipid The crazy thing about this itching is that this is the 3rd attempt back on the plaquenil and with the 1st two tries I had no itching but different side effects that made me discontinue it. The 1st time I was on it brand name 400 mg. for 8 months and had to d/c due to terrible intestinal cramping and tinnitus. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How long do side effects of plaquenil last Plaquenil Side Effects on Your Eyes and Vision, Common and Rare Side Effects for Plaquenil Oral Chloroquine inhibits autophagic flux by decreasing autophagosome lysosome fusionHydroxychloroquine pregnancyPlaquenil insertWhat is chloroquine in lysosomesHydroxychloroquine reviews eyes Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Will you have Withdrawal syndrome with Plaquenil - eHealthMe. Plaquenil - how long for side effects to subside?. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Incidence not known. Blistering, peeling, loosening of the skin. blurred vision or other vision changes. chest discomfort, pain, or tightness. cough or hoarseness. dark urine. decreased. This can be a normal side effect from the plaquenil and it usually lasts a couple of weeks until your body adjusts to it. Try to stick it out, continue taking the compazine but know that that med itself causes drowsiness. You may want to ask for Zofran which doesnt make you as you take it before bed. I still believe this to be true, but I am convinced now that plaquenil must have multiple modes of action, one being long term effects, and one being something happening in the short term. There is no way what I experienced over the last 4 days was due to placebo affect. By last night, I was so achy, tired, trouble breathing still, etc.