Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Treated with primaquine and chloroquine Plaquenil liver kidney toxicity lyme Generic of hydroxychloroquine sulfate Methotrexate is a liquid injection medication I use for my RA. This was prescribed to my by my rhumotologist on 10/10/09. I originally started seeing her for my Lupus. I was also prescribed plaquenil, and folate acid. Of course the doseage of all the meds was low. Apr 21, 2017 I had to stop methotrexate about 7 months ago for my RA, due to bad side effects after using it successfully for 10 years. As an alternative, my rheumy put me on HCQS, also known as plaquenil, along with. I had to stop methotrexate about 7 months ago for my RA, due to bad side effects after using it successfully for 10 years. As an alternative, my rheumy put me on HCQS, also known as plaquenil, along with 5mg of prednisone. But ever since then I've had the runs something terrible, and whatever I do or don't do I can't seem to shake it. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. How to switch from plaquenil to methotrexate Plaquenil Uses, Dosage & Side Effects -, Plaquenil aka HCQS – Anyone on this getting severe diarrhea. Chloroquine resistant malaria usmle Hello hope everyone is well just a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. Methotrexate and plaquenil -. Plaquenil aka HCQS – Anyone on this getting severe.. Changing from methotrexate and prednisone to methotre.. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in.