Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Imuran plaquenil together Hydroxychloroquine and neuropathy Dec 15, 2017 Skin discolouration or hyperpigmentation is a sign of underlying health problems. Skin, the largest organ of the human body, is a mirror of your health. So whenever something goes wrong inside, it eventually starts reflecting on the skin. One such sign is hyperpigmentation, a sign from your skin that all is not well within your body. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine -sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Jan 15, 2020 Plaquenil and Skin hyperpigmentation - a real-world study. Summary Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Chloroquine hyperpigmentation Hydroxychloroquine‐induced hyperpigmentation, The Journal., Hydroxychloroquine - Wikipedia Chloroquine resistant vivax malaria treatment Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Skin Pigmentation with Hydroxychloroquine Plaquenil.. Will you have Skin hyperpigmentation with Plaquenil - eHealthMe. Hydroxychloroquine-Induced Hyperpigmentation JCR Journal.. Toxic effect of chloroquine and advised to avoid direct exposure to sunlight. Keywords Chloroquine, Hyperpigmentation of skin, Connective tissue disorder Chloroquine has affinity for melanin and it gets con-centrated in pigmented melanin-containing structures which may explain its toxic effects on the eye kerato- Hydroxychloroquine-induced pigmentation lesions usually begin after a few months or years of treatment. When we compared our patients with the controls, we found no significant association with the duration of HCQ treatment or with the cumulative dose of HCQ. Oct 30, 2008 Rare, previous reports of hyperpigmentation indicate the presence of both melanin and hemosiderin in patients being treated with antimalarial medication. To our knowledge, this staining pattern for hydroxychloroquine has not been previously reported in the literature and supports that hydroxychloroquine, in addition to chloroquine, binds to melanin.