It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine medline plus Plaquenil recent findings sandoz brand How does hydroxychloroquine work in sle Health benefits of plaquenil Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Hydroxychloroquine or Plaquenil is a medication used widely in systemic lupus erythematosus SLE or lupus. It’s really considered quite a gentle immune modulating medication and it’s cheap, so rheumatologists use it a lot to try and help the symptoms patients present with. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine -sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine in sle Hydroxychloroquine Uses, Dosage & Side Effects -, Hydroxychloroquine in SLE you need a good reason NOT to be using it Hydroxychloroquine 12.5mg To the Editor The Canadian Hydroxychloroquine Study Group deserves credit for its attempt to test the effectiveness of hydroxychloroquine in systemic lupus erythematosus Jan. 17 issue.1 Unfortun. Hydroxychloroquine in Systemic Lupus Erythematosus NEJM. Hydroxychloroquine - Wikipedia. In SLE Patients, Antimalarial Medication Seen to Reduce Inflammation. INTRODUCTION Hydroxychloroquine HCQ is an alkalinizing lysosomatropic drug that accumulates in lysosomes where it inhibits some important functions by increasing the pH. HCQ has proved to be effective in a number of autoimmune diseases including systemic lupus erythematosus SLE. Dec 17, 2018 Of these, B2GPI may be the most relevant target of the antiphospholipid antibodies. Physicians prescribe hydroxychloroquine to treat systemic lupus erythematosus SLE, and it has been shown to have anti-thrombotic effects in SLE patients. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.