Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Does plaquenil help reflux Plaquenil and pregnancy risk Hydroxychloroquine-induced bull's eye maculopathy Previous Article The crisis of inadequate treatment in osteoporosis A woman aged 28 years with systemic lupus erythematous and abnormal kidney function, treated with 45 mg/kg hydroxychloroquine daily for 15 years cumulative dose 1369 g, presented with bilateral progressive central vision. Hydroxychloroquine or chloroquine ingestion can cause atrophy of the retinal pigment epithelium in the form of a bull’s eye maculopathy in cases of chronic use. Early detection of toxicity prior to the development of the bull’s eye is important, as loss of visual acuity is usually irreversible at that stage. Bull’s-Eye Maculopathy Associated with Hydroxychloroquine Article in New England Journal of Medicine 380171656-1656 April 2019 with 6 Reads How we measure 'reads' While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Bull's eye maculopathy hydroxychloroquine Drug induced maculopathy by Dr Jay Chhablani, Macular Telangiectasia A cause of bull’s eye maculopathy Dengue virus chloroquineHydroxychloroquine 200 mg tabDiscoid lupus plaquenilPlaquenil visual side effects On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful. Hydroxychloroquine-Induced Retinal Toxicity - American.. Bull’s-Eye Maculopathy Associated with Hydroxychloroquine. Bull's Eye Maculopathy – Causes, Complications, and.. Bull's eye maculopathy maculopathy, bull's eye An ocular condition in which degeneration of the retinal pigment epithelium in the macular area causes alternating ring-like light and dark zones of pigmentation, as in a target. Bull’s eye maculopathy describes a number of different conditions in which there is a ring of pale-looking damage around a darker area of the macula. The macula can often appear to have circular bands of different shades of pink and orange. Age of onset and severity of sight loss varies, and it can be inherited in many ways. Torpedo maculopathy; Diagnosis Bull’s eye maculopathy presumed Hydroxychloroquine toxicity RELE Management Updated single-vision intermediate lenses were recommended for computer work in order to maximise the patient’s field of view. Although she has discontinued Plaquenil, a report identifying these adverse effects was sent to the.