Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine phosphate 250 mg day What to expect when taking plaquenil for the first time Hydroxychloroquine macular toxicity Plaquenil and dental implants Hydroxychloroquine is dispensed as 200 mg tablets, which is equivalent to 155 mg of the base. Hydroxychloroquine should be taken with a meal or a glass of milk to minimise the gastrointestinal side effects. Alternate-day dosing can be used. Possible explanations for these findings are that HCQ/CQ-prescribing providers may be unfamiliar with ocular side effects of long-term use or the patient characteristics associated with high risk for macular toxicity, or they may not appreciate the usefulness of pre-emptive screening, before vision is lost. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Long term side effects hydroxychloroquine Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center, Are Long-Term Chloroquine or Hydroxychloroquine. - PubMed Central PMC Plaquenil hydroxychloroquine ocdDoes plaquenil cause weight gain or lossHydroxychloroquine induced cardiomyopathy in systemic lupus erythematosus Hydroxychloroquine oral tablet is used for short-term treatment of malaria, but it may be used for long-term treatment of lupus or rheumatoid arthritis. Hydroxychloroquine comes with risks if you. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Oral Uses, Side Effects, Interactions, Pictures.. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What is the most important information I should know about hydroxychloroquine Plaquenil, Plaquenil Sulfate, Quineprox? Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Long-term studies in animals have not been conducted to evaluate the carcinogenic potential of Plaquenil. The mutagenic potential of hydroxychloroquine was not evaluated. However, chloroquine has been shown to be a catalytic inhibitor of DNA repair enzymes topoisomerase II and to produce weak genotoxic effects through this mode of action.