Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Cipro and plaquenil Hydroxychloroquine sulfate 200 Uronema chloroquine phosphate How long do plaquenil side effects last Summary Constipation is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Enbrel, and have Osteoporosis. The incidence of new-onset or flaring psoriasis associated with Plaquenil varies from 0-100% depending on which case series report you read! Allergic and psoriasis-like rashes tend to develop within the first few weeks or months of starting Plaquenil. If Plaquenil helps a serious chronic disease such as lupus, it may be taken for years. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and constipation Plaquenil and explosive bowel movements, Plaquenil Use in Autoimmune Diseases Plaquenil rash skinChloroquine inhibits autophagy in host tissues NSAIDS - or non steroidal anti inflammatory drugs such as Motrin, are often very irritating to the stomach and intestines. Other medications frequently used in treating Sjogren's Syndrome such as Plaquenil and Methotrexate may cause stomach upset. Reasonably Well Gastrointestinal Effects of Sjogren's Syndrome. Plaquenil Side Effects Common, Severe, Long Term -. Hydroxychloroquine Sulfate Constipation Reports - DrugInformer. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Re Prednisone, plaquenil and constipation. I haven't experienced any problems with constipation while on prednisone and plaquenil. I had a lot of bowel trouble before I was DXD though, which may be why I am not having problems now, could be that the drugs just evened me out so to speak.